Metastatic Merkel Cell Carcinoma Market Trends, Growth Opportunities and Challenges, Clinical Developments, Leading Companies, Emerging Therapies, and Epidemiology Forecast

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Metastatic Merkel Cell Carcinoma Market Trends, Growth Opportunities and Challenges, Clinical Developments, Leading Companies, Emerging Therapies, and Epidemiology Forecast

August 05
02:05 2021
Metastatic Merkel Cell Carcinoma Market Trends, Growth Opportunities and Challenges, Clinical Developments, Leading Companies, Emerging Therapies, and Epidemiology Forecast

Delveinsight Business Research LLP

DelveInsight’s “Metastatic Merkel Cell Carcinoma Market Insights, Epidemiology, and Market Forecast 2030” report delivers an in-depth understanding of the historical and forecasted epidemiology as well as the Metastatic Merkel Cell Carcinoma Market Size and Share in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and Japan.

The Metastatic Merkel Cell Carcinoma Market Research Report covers emerging drugs, current treatment practices, market share of the individual therapies, current and forecasted Metastatic Merkel Cell Carcinoma market Size from 2017 to 2030 segmented by seven major markets. 

The report provides a detailed current Metastatic Merkel Cell Carcinoma treatment practice/algorithm, market drivers, market barriers, and unmet medical needs to curate the best of the opportunities and assess the underlying potential of the market. 

Metastatic Merkel Cell Carcinoma Market

Merkel Cell Carcinoma (MCC) is a rare, highly aggressive neuroendocrine cutaneous neoplasm with a variable clinical presentation. It is a predominantly dermal-based lesion composed of monotonous small round cells with scanty cytoplasm, often difficult to differentiate from small round cell tumors, metastatic small cell carcinoma, blastic hematologic malignancies, and melanoma.

Treatment of stage IV Merkel cell carcinoma may include the following: Immunotherapy (immune checkpoint inhibitor therapy using avelumab or pembrolizumab). Chemotherapy, surgery or radiation therapy as palliative treatment to relieve symptoms and improve quality of life.

Metastatic Merkel Cell Carcinoma Market Key Facts

  • As per DirkSchadendorf et al. (2016), In a study of over 14,000 patients, 50.6% of patients presented with local disease, 35.4% with nodal disease, and 13.5% with distant metastatic MCC.

  • As per the study conducted by Kelly G. Paulson et al. (2017), Merkel cell carcinoma (MCC) is a neuroendocrine skin cancer with high metastatic potential, with one-third to one-half of patients developing recurrence or metastasis.

  • According to João Pedreira Duprat, et al. (2011), the estimated annual incidence of MCC is 0.23 per 100,000 individuals for Caucasians, whereas the incidence in those of African descent is 0.01 per 100,000 and appears to be even lower in Polynesians.

  • As per the National Organization for Rare Disorders 2019: Approximately 60% of MCC tumors arise in men. In the past 15 years, the incidence has tripled in the United States, and it can be lethal for about one-third of the people affected.

  • As of 2015, approximately 2500 persons per year are diagnosed with this cancer in the United States.

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 Key Benefits of Metastatic Merkel Cell Carcinoma Market Report

  • The market report provides an in-depth analysis of Metastatic Merkel Cell Carcinoma Market Size, Share, Trend, and Epidemiology Forecast till 2030 in the seven major markets (i.e. the United States, EU5 (Germany, Italy, Spain, France, and the UK) and Japan.

  • The report will help in developing business strategies by understanding the Metastatic Merkel Cell Carcinoma Market Trends, recent developments, key players, and future market competition that will shape and drive the market growth in the upcoming years.

  • The market report covers the Metastatic Merkel Cell Carcinoma current treatment practices, emerging drugs, market share of the individual therapies in the seven major markets.

  • The report provides a detailed assessment of the Metastatic Merkel Cell Carcinoma market in terms of market drivers & barriers, unmet needs, market opportunities, patient population, detailed comparative analysis of pipeline products including clinical and non-clinical stage products, and other factors. 

Metastatic Merkel Cell Carcinoma Market 

Metastatic Merkel Cell Carcinoma Market Size is anticipated to increase during the study period owing to the rise in the number of Incident population of Metastatic Merkel Cell Carcinoma patients in the 7MM. Extensive R&D activities by academias and industries and the expected launch of therapies will also fuel the growth of the market.

The market outlook section of the report helps to build a detailed comprehension of the historic, current, and forecasted Metastatic Merkel Cell Carcinoma market size and share by analyzing the impact of current therapies on the market, unmet needs, drivers, and barriers, and demand for better technology.

The report gives a thorough detail of the Metastatic Merkel Cell Carcinoma market trend of each marketed drug and late-stage pipeline therapy by evaluating their impact based on the annual cost of therapy, inclusion and exclusion criteria, mechanism of action, increasing patient pool, covered patient segment, expected launch year, competition with other therapies, brand value, their impact on the market and view of the key opinion leaders.

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Metastatic Merkel Cell Carcinoma Epidemiology

The epidemiology section covers insights about the historical and current Metastatic Merkel Cell Carcinoma patient pool and forecasted trends for every seven major countries from 2017 to 2030. It helps to recognize the causes of current and forecasted trends by exploring numerous studies and views of key opinion leaders. The epidemiology section also provides the diagnosed patient pool and their trends along with assumptions undertaken.  

Metastatic Merkel Cell Carcinoma Drugs Uptake and Pipeline Development Activities

The drugs uptake section focuses on the rate of uptake of the potential drugs recently launched in the Metastatic Merkel Cell Carcinoma market or expected to get launched in the market during the study period. The analysis covers Metastatic Merkel Cell Carcinoma market uptake by drugs; patient uptake by therapies; and sales of each drug.   

Report’s Drugs Uptake section helps in understanding the drugs with the most rapid uptake, reasons behind the maximal use of new drugs and allow the comparison of the drugs on the basis of market share and size which again will be useful in investigating factors important in market uptake and in making financial and regulatory decisions.

The report also covers the Metastatic Merkel Cell Carcinoma Pipeline Development Activities and provides valuable insights about different therapeutic candidates in Phase II, and Phase III stages and the key companies in the market involved in developing targeted therapeutics. It also analyses the recent Development such as collaborations, acquisitions, and mergers, licensing patent details, and other information for emerging therapies.

Globally, various companies  are involved in developing effective therapies for Metastatic Merkel Cell Carcinoma and further progress in the research and development is likely to translate into a real improvement in the treatment options for Metastatic Merkel Cell Carcinoma

Metastatic Merkel Cell Carcinoma Companies:

  • Merck

  • Morphogenesis

  • NantKwest

  • Kartos Therapeutics

  • Incyte Corporation

And others

Metastatic Merkel Cell Carcinoma Therapies covered in the report include:

  • IFx-Hu2.0

  • Nivolumab + Ipilimumab

  • INCMGA00012

  • haNk and aNK cell therapies

And many more.

Table of Content

1. Key Insights

2. Executive Summary 

3. Metastatic Merkel Cell Carcinoma Competitive Intelligence Analysis

4. Metastatic Merkel Cell Carcinoma Market Overview at a Glance

5. Metastatic Merkel Cell Carcinoma Disease Background and Overview

6. Metastatic Merkel Cell Carcinoma Patient Journey

7. Metastatic Merkel Cell Carcinoma Epidemiology and Patient Population

8. Metastatic Merkel Cell Carcinoma Treatment Algorithm, Current Treatment, and Medical Practices

9. Metastatic Merkel Cell Carcinoma Unmet Needs

10. Key Endpoints of Metastatic Merkel Cell Carcinoma Treatment

11. Metastatic Merkel Cell Carcinoma Marketed Products

12. Metastatic Merkel Cell Carcinoma Emerging Therapies

13. Metastatic Merkel Cell Carcinoma Seven Major Market Analysis

14. Attribute Analysis

15. Metastatic Merkel Cell Carcinoma Market Outlook (7 major markets)

16. Metastatic Merkel Cell Carcinoma Access and Reimbursement Overview

17. KOL Views on the Metastatic Merkel Cell Carcinoma Market.

18. Metastatic Merkel Cell Carcinoma Market Drivers

19. Metastatic Merkel Cell Carcinoma Market Barriers

20. Appendix

21. DelveInsight Capabilities

22. Disclaimer

*The table of contents is not exhaustive; the final content may vary. 

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About DelveInsight
DelveInsight is a leading Business Consultant, and Market Research Firm focused exclusively on life sciences. It supports pharma companies by providing end-to-end comprehensive solutions to improve their performance.

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